Table 1 The parameters used in this paper come from10,11.
From: Delay-aware chemotherapy dosing via online critic learning
Parameter | Description | Value | Unit |
|---|---|---|---|
\(a_1\) | Immune cell kill rate | 0.2 | \(\hbox {mg}^{-1}\) L \(\hbox {day}^{-1}\) |
\(a_2\) | Tumor cell kill rate | 0.3 | \(\hbox {mg}^{-1}\) L \(\hbox {day}^{-1}\) |
\(a_3\) | Normal cell kill rate | 0.1 | \(\hbox {mg}^{-1}\) L \(\hbox {day}^{-1}\) |
\(b_1\) | Reciprocal carrying capacity of tumor cells | 1 | \(\hbox {cell}^{-1}\) |
\(b_2\) | Reciprocal carrying capacity of normal cells | 1 | \(\hbox {cell}^{-1}\) |
\(c_1\) | Immune cell competition term | 1 | \(\hbox {cell}^{-1}\) \(\hbox {day}^{-1}\) |
\(c_2\) | Tumor cell competition term | 0.5 | \(\hbox {cell}^{-1}\) \(\hbox {day}^{-1}\) |
\(c_3\) | Tumor-normal cell competition term | 1 | \(\hbox {cell}^{-1}\) \(\hbox {day}^{-1}\) |
\(c_4\) | Normal-tumor cell competition term | 1 | \(\hbox {cell}^{-1}\) \(\hbox {day}^{-1}\) |
\(d_1\) | Immune cell death rate | 0.2 | \(\hbox {day}^{-1}\) |
\(d_2\) | Decay rate of injected drug | 1 | \(\hbox {day}^{-1}\) |
\(r_1\) | Tumor cell growth rate | 1.5 | \(\hbox {day}^{-1}\) |
\(r_2\) | Normal cell growth rate | 1 | \(\hbox {day}^{-1}\) |
s | Immune cell influx rate | 0.33 | cell \(\hbox {day}^{-1}\) |
\(\alpha\) | Immune threshold rate | 0.3 | cell |
\(\rho\) | Immune response rate | 0.01 | \(\hbox {day}^{-1}\) |
