Table 2 Baseline characteristics.

From: Immunosuppressive therapy in patients with biopsy-proven inflammatory myocardial disease: a systematic review and meta-analysis

 

Hazebroek et al.13

Wojnicz et al.15

Frustaci et al.16

Schultheiss et al.17

Parrillo et al.18

Poloczkova et al.14

Mason et al.19

Treatment

Control

Treatment

Control

Treatment

Control

Treatment 1 (4MIU)

Treatment 2 (8MIU)

Control

Treatment

Control

Treatment

Control

Treatment

Control

No. of patients randomized

26

24

41

43

43

42

49

46

47

49

53

9

11

64

47

No. of patients who completed the study

26

24

28

30

43

42

131*

49

52

9

11

NA

Age (years)

54 ± 13

53 ± 9

41 mean (16,61; 95% CI)

39 mean (29,60; 95% CI)

44.2 ± 15.8

41.1 ± 15.1

47.4 ± 12.3

53.1 ± 10.3

51.4 ± 11.1

43 mean (23,67; 95% CI)

46.1 ± 7.3**

43 ± 14

41 ± 13

Female sex (%)

23%

21%

21.95%

13.95%

41%

38%

24.5%

39.1%

45.8%

NA

10% **

42.2%

31.9%

I (NYHA)

NA

NA

0

0

0

0

0

0

0

NA

2.2 ± 0.4***

2.1 ± 0.3***

14.5%

15.6%

II (NYHA)

NA

NA

8 (19.51%)

15 (34.88%)

22 (51%)

26 (62%)

27 (55%)

28 (61%)

34 (72%)

NA

38.7%

28.9%

III (NYHA)

1 (4%)

0 (0%)

29 (70.73%)

26 (60.46%)

15 (35%)

12 (29%)

18 (37%)

18 (39%)

13 (28%)

NA

38.7%

42.2%

IV (NYHA)

4 (9.75%)

2 (4.65%)

6 (14%)

4 (9%)

1 (2%)

0

1 (2%)

NA

8.1%

13.3%

LVEF (%)

36 ± 7

35 ± 6

23.8 ± 8.6

24.9 ± 7.3

26.5 ± 6.6

27.7 ± 6.4

45 ± 12.4

43.2 ± 10.5

44.1 ± 10.6

17.9 ± 1.0

17.1 ± 1.1

22.3 ± 4.7

21.7 ± 4.0

24 ± 11.0

24 ± 9.0

LVEDD (mm)

NA

NA

65.6 ± 8.6

68.5 ± 8.0

68.4 ± 7.0

68.9 ± 7.5

57.5 ± 10.7

58.8 ± 7.8

60 ± 9.6

69.8 ± 1.4

67.7 ± 1.0

64.0 ± 8.9

64.8 ± 7.0

NA

NA

Atrial fibrillation, n (%)

5 (19%)

10 (42%)

11 (26.8%)

14 (32.5%)

NA

NA

8.7%

6.3%

12.2%

NA

NA

NA

NA

NA

NA

Presence of bundle branch block

5 (19%) (LBBB)

6 (25%) (LBBB)

NA

NA

5 (12%) (LBBB)

8 (19%) (LBBB)

13.0%

12.5%

10.2%

NA

NA

NA

NA

NA

NA

  1. Overview table containing baseline characteristics of included studies. DCM dilated cardiomyopathy, LVEF left ventricular ejection fraction, NYHA New York Heart Association Classification, LVEDD left ventricular end-diastolic diameter, LBBB left bundle branch block, NA not answered. *12 patients did not complete the study (no information about their arm). **mean age with standard deviation only given for the whole group. ***NYHA class given in mean + standard deviation, no further division.
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