Table 3 Bleeding score with respect to platelet activation status in ITP patients.
Characteristics | Bleeding Score | N | Mean ± SD | Median (Min-Max) | P-value* | AUC (95%CI) | Cut-off value | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|---|---|
Age | 1 | 10 | 25.8 ± 9.23 | 24.00 (16–40) | 0.023 | 76.4 (58.5–94.3) | 15 | 61.1 | 100 |
2 | 18 | 17.83 ± 10.57 | 11.00 (10–39) | ||||||
P-selectin (Base) | 1 | 10 | 1.88 ± 1.18 | 1.55 (1.02–5.1) | 0.137 | 67.5 (45.9–89.1) | 1.745 | 61.1 | 80.0 |
2 | 18 | 2.46 ± 1.5 | 1.85 (1.18–6.45) | ||||||
PAC-1 (Base) | 1 | 10 | 1.92 ± 0.3 | 1.83 (1.55–2.43) | 0.533 | 57.5 (33.6–81.4) | 2.015 | 83.3 | 40.0 |
2 | 18 | 1.86 ± 0.32 | 1.77 (1.56–2.9) | ||||||
ROS (Base) | 1 | 10 | 1.82 ± 0.51 | 1.61 (1.17–2.7) | 0.280 | 62.8 (40.6–84.9) | 1.475 | 55.6 | 80.0 |
2 | 18 | 1.64 ± 0.51 | 1.47 (1.07–2.88) | ||||||
P-sel (PMA) | 1 | 10 | 5.05 ± 1.65 | 4.58 (3.39–8.52) | 0.013 | 81.4 (65.4–97.4) | 3.36 | 61.1 | 100.0 |
2 | 18 | 3.38 ± 1.07 | 3.10 (2–5.68.68) | ||||||
PAC-1 (PMA) | 1 | 10 | 3.01 ± 1.1 | 2.65 (1.95–5.95) | 0.113 | 68.6 (45.6–91.6) | 2.625 | 83.3 | 60.0 |
2 | 18 | 2.35 ± 0.35 | 2.46 (1.61–2.8) | ||||||
ROS (PMA) | 1 | 10 | 7.41 ± 1.8 | 7.12 (5.43–9.6) | 0.015 | 78.3 (60.2–96.4) | 8.020/5.415** | 100/50** | 50/100** |
2 | 18 | 5.76 ± 1.32 | 5.53 (3.62–7.89) | ||||||
PLT count | 1 | 10 | 101.8 ± 75.68 | 68.50 (28–207) | 0.160 | 66.7 (44.1–89.3) | 186.5 | 100 | 30.0 |
2 | 18 | 58.06 ± 43.4 | 48.00 (12–171) |
