Table 1 27 species glycerophospholipids and sphingolipids features and their alteration in Tmem63AG167E/G167E rats.

From: Spatial lipidomics reveals altered lipid profiles in TMEM63A mutant rats with hypomyelination

LCMS

white matter-rich regions

gray-white matter junctions

gray matter-rich regions

CS

CC

TH

CSt

hTH

CeC

CBC

HC

MB

PC(15:0/18:2)

-

-

 

-

-

  

-

-

PC(18:2/16:1)

   

-

-

-

 

-

 

PC(15:0/20:2)

+

+

+

      

PC(18:0/18:1)

 

+

       

PC(18:0/20:3)

-

-

-

-

     

PC(20:4/20:5)

-

-

-

-

     

PC(20:0/20:3)

-

-

-

      

PC(20:0/22:0)

 

+

       

LPC(O-18:0/0:0)

   

-

     

PE(P-16:0/18:1)

-

-

       

PE(14:0/18:0)

-

-

-

      

PE(15:0/20:2)

-

-

-

  

-

   

PE(18:0/18:1)

  

-

-

    

-

PE(P-18:0/20:1)

-

-

-

      

PE(16:0/22:4)

-

-

      

-

LPE(0:0/16:1(9Z))

   

+

 

+

   

LPE 20:4

        

-

PS(18:0/18:1)

-

-

    

-

  

PS(18:0/22:6)

-

-

       

PA(16:0/16:0)

-

-

 

-

     

LPA(13:0)

 

-

 

-

-

  

-

-

GPC

+

+

+

   

+

+

+

Sphingosine

   

-

-

 

-

-

 

GlcCer(d18:1/26:1)

-

-

-

      

GlcCer(d18:1/24:1)

-

-

-

-

     

LacCer(d18:1/16:0)

-

-

-

-

     

SGCer(d18:1/14:0)

 

-

 

-

-

  

-

-

  1. +, increase; -, decrease; CS, cerebellum stem; CC, corpus callosum; TH, thalamus; CSt, corpus striatum; hTH, hypothalamus; CeC, cerebral cortex; CBC, cerebellar cortex; HC, hippocampus; MB, midbrain.