Table 2 Results of GO and KEGG enrichment analysis for LMRDEGs.

From: Lactate metabolism–related differentially expressed genes reveal biological mechanisms underlying sarcopenia

ONTOLOGY

ID

Description

Generatio

Bgratio

p-value

adj.p

q-value

BP

GO:0006091

generation of precursor metabolites and energy

7/17

494/18,800

1.28333E-07

6.20492E-05

3.40421E-05

BP

GO:0010506

regulation of autophagy

6/17

336/18,800

3.26719E-07

0.000105313

5.77778E-05

BP

GO:0046034

ATP metabolic process

5/17

273/18,800

3.33899E-06

0.000645761

0.000354285

BP

GO:0044262

cellular carbohydrate metabolic process

5/17

287/18,800

4.26318E-06

0.000687082

0.000376955

BP

GO:1,901,652

response to peptide

5/17

491/18,800

5.68035E-05

0.002762887

0.001515806

MF

GO:0031490

chromatin DNA binding

3/17

105/18,410

0.000115663

0.01110367

0.006452791

KEGG

hsa04922

Glucagon signaling pathway

3/12

107/8164

0.000441873

0.017963539

0.013015278

KEGG

hsa04066

HIF-1 signaling pathway

3/12

109/8164

0.000466585

0.017963539

0.013015278

KEGG

hsa00640

Propanoate metabolism

2/12

32/8164

0.000958646

0.024605247

0.017827452

KEGG

hsa00620

Pyruvate metabolism

2/12

47/8164

0.002063865

0.03346945

0.024249909

KEGG

hsa00270

Cysteine and methionine metabolism

2/12

51/8164

0.002426315

0.03346945

0.024249909

  1. GO, Gene ontology; BP, Biological process; CC, Cellular component; MF, Molecular function; KEGG, Kyoto encyclopedia of genes and genomes; LMRDEGs, Lactate metabolism-related differentially expressed genes