Fig. 3
Effect of 1 µM nisoldipine (NISO), 1 µM KN-93, and 3 µM H-89, on the parameters of IKs under baseline conditions. (A) Command action potential (above) and representative averaged IKs current traces (below) obtained under APVC conditions in untreated controls, in the presence of 1 µM NISO (blue), 1 µM KN-93, and 3 µM H-89. (B) Mid-plateau current densities, (C) peak current densities, and (D) current integrals under the conditions on panel (A). Symbols and bars are mean ± SEM, small dots represent individual data, numbers in parenthesis indicate the number of cells studied. Asterisks indicate significant differences (p < 0.05) between groups determined using Dunnett’s post-hoc test comparing data to the control group.
