Table 2 Synthesis of 2(a-l) by ChCl/HCA-DES.

From: The choline chloride/hydroquinone carboxylic acid-based DES as a novel catalyst for the green synthesis of dihydrochromeno[4,3-d]pyrimidinediones

Entry

Aldehyde

Product

Time

(min)

Yield

(%)

M.P. °C Found

M.P. °C literature

TON

[a]

TOF

[(b]

1

2a

25

90

155–165

160-16225

90

3.6

2

2b

30

95

163–173

195-19725

95

3.16

3

2c

35

83

270–276

268-27031

83

2.37

4

2d

20

85

180–197

172-17425

85

4.25

5

2e

25

95

199–220

242-24532

95

3.8

6

2f

30

86

179–181

180-18227

86

2.86

7

2 g

20

87

185–235

248-25033

87

4.35

8

2 h

35

88

175–185

NEW

88

2.51

9

View full size image

2i

20

90

215–220

210-21234

90

4.5

10

2j

20

95

180–185

260-26235

95

4.75

11

2k

15

96

281–283

285-28727

96

6.4

12

2 L

20

95

160–167

170-17127

95

4.75

  1. [a]: TON = moles of catalyst/moles of product.
  2. [b]: TOF = TON/time.