Table 3 Serum antibody titers (1:X) in rhesus monkeys after intravenous injection of lyophilized hepatitis A live attenuated Vaccine.

From: Immunogenicity and safety in animals of a lyophilized live attenuated hepatitis A vaccine following stabilizer optimization

Group

Time

Dā‚€ to Dā‚‚ā‚ˆ Antibody increase (fold)

Number immunized

Number seroconverted

Seroconversion rate (%)

Dā‚€

Dā‚ā‚„

Dā‚‚ā‚

Dā‚‚ā‚ˆ

Negative Control Group

1F01

1

2

2

2

2

2

0

0

1M01

1

4

2

1

1

Group Geometric Mean

1.0

2.8

2.0

1.4

1.4

/

/

/

Commercial Control Group

2F01

2

4

16

256

128

5

5

100

2F02

2

4

16

128

64

2M01

2

2

2

32

16

2M02

2

2

4

256

128

2M03

1

4

4

256

256

Group Geometric Mean

1.7

3.0

6.1

147.0

84.4

/

/

/

Test Group

3F01

4

32

128

128

32

5

5

100

3F02

4

8

16

1024

256

3M01

2

2

32

512

256

3M02

2

16

32

32

16

3M03

2

2

8

64

32

Group Geometric Mean

2.6

7.0

27.9

168.9

64.0

/

/

/

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