Table 1 Animal groups.
Group 1(Sham) | Rats received carboxymethylcellulose (CMC) orally with abdominal incision without HIR |
|---|---|
Group 2 (Sham + Ap10) | Rats received Aprepitant 10 mg/kg suspended in CMC orally17 daily for 5 consecutive days16 before abdominal incision without HIR |
Group 3 (HIR) | Rats received CMC with laparotomy and occlusion of hepatic blood supply by pringle maneuver for 30 min followed by reperfusion for one hour |
Group 4 (Ap5 + HIR) | Rats received Aprepitant 5 mg/kg suspended in CMC orally daily for 5 consecutive days before HIR18 |
Group 5 (Ap10 + HIR) | Rats received Aprepitant 10 mg/kg suspended in CMC orally daily for 5 consecutive days before HIR18 |
Group 6 (Ap20 + HIR) | Rats received Aprepitant 20 mg/kg suspended in CMC orally daily for 5 consecutive days before HIR18 |
