Table 2 Genomic DNA damage induction in human pancreatic cancer (PANC-1) cells following exposure to Ca(OH)2 NPs at the IC50 concentration (152.40 µg/ml) for 72 h.

From: Calcium hydroxide nanoparticles induce apoptotic cell death in human pancreatic cancer cells through over ROS-driven genomic instability and mitochondrial dysfunction

Cells

Treatment (µg/ml)

Tail length (px)

%DNA in tail

Tail moment

PANC-1 cells

Ca(OH)2 NPs (0.00)

4.20 ± 0.55

16.65 ± 1.82

0.70 ± 0.15

Ca(OH)2 NPs (152.40)

14.35 ± 1.94**

31.90 ± 1.95**

4.37 ± 0.50***

  1. Results are expressed as mean ± SD.
  2. **, ***: Indicates statistical significant difference from the compared untreated control cells at p < 0.01 and p < 0.001, respectively, using independent student t-test.
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