Table 3 The expression level of apoptotic p53, mitochondrial ND3 and anti-apoptotic Bcl2 genes in human pancreatic cancer (PANC-1) cells following exposure to Ca(OH)2 NPs at the IC50 concentration (152.40 µg/ml) for 72 h.

From: Calcium hydroxide nanoparticles induce apoptotic cell death in human pancreatic cancer cells through over ROS-driven genomic instability and mitochondrial dysfunction

Cells

Treatment (µg/ml)

p53

ND3

Bcl2

PANC-1 cells

Ca(OH)2 NPs (0.00)

1.00 ± 0.00

1.00 ± 0.00

1.00 ± 0.00

Ca(OH)2 NPs (152.40)

11.07 ± 1.76**

2.38 ± 0.12***

0.58 ± 0.07**

  1. Results are expressed as mean ± SD.
  2. **, ***: Indicates statistical significant difference from the compared untreated control cells at p < 0.01 and p < 0.001, respectively, using independent student t-test.
Back to article page