Fig. 3 | Scientific Reports

Fig. 3

From: Signs of immune dysregulation in second-trimester maternal blood RNA profiles in late-onset preeclampsia

Fig. 3

Heatmaps showing differential second-trimester pathway activation in women with late-onset preeclampsia and normotensive women. Shown are the major upregulated pathways in preeclampsia (PE) related to (a) leukocyte transendothelial migration, (b) JAK-STAT signaling, (c) systemic lupus erythematosus (SLE) and (d) graft versus host disease pathways. Columns represent samples (ordered by rotated values in each principal component, PC), and rows represent pathway genes (ordered by loading values in each PC), with the left indicating leading genes. Red color indicates upregulation, and blue indicates downregulation, normalized across preeclampsia (red) and normotensive pregnancies (blue).

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