Fig. 4

Performances of three candidate genes for late-onset preeclampsia prediction. (a) ROC curves show the performance of selected biomarkers in distinguishing preeclampsia (PE) and normotensive pregnancies (NP) with false positive rate (FPR) on the x-axis and true positive rate (TPR) on the y-axis. The area under curve (AUC) values and corresponding p-values (testing whether AUC > 0.5) provide a measure of the diagnostic power of each biomarker. (b) Violin plots showing variation, with p-value from the two-sided Wilcoxon test shown above, in gene expression of the same biomarkers between PE and NP. Horizontal lines indicate median expression.