Fig. 6 | Scientific Reports

Fig. 6

From: Network toxicology, transcriptomics, and cytotoxic validation reveal TDCPP-induced pterygium mechanisms

Fig. 6

Results of cell morphology, cell viability assay, and MMP3 expression after TDCPP exposure.A. Growth morphology of the control group cells. B. Cell growth morphology in the 0.5 µM TDCPP exposure group. C. Cell growth morphology in the 50 µM TDCPP exposure group. D. The results of the CCK − 8 assay. TDCPP (0.5, 1, 1.5, 5, and 50 µM) in the culture medium, culturing conjunctival fibroblasts under 0.5 µM and 1 µM conditions could enhance their viability, while viability decreased under 50 µM conditions. E. Under 0.5 µM TDCPP exposure, the expression level of the MMP3 gene in conjunctival fibroblasts of the experimental group was significantly increased compared with that in the control group.

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