Table 3 Coagulation parameters during ECMO therapy.

From: Acquired factor XIII deficiency in adult patients during ECMO: a prospective observational study

Coagulation parameter

Unit

Minimum

Maximum

Platelet count

G/L

51 (38–70)

145 (117–195)

Antithrombin III activity

%

54 (44–69)

113 (99–128)

D-dimer

µg/mL

1.7 (0.9–4.1)

21 (7.6–35.2)

Fibrinogen

mg/dL

222 (182–369)

704 (594–900)

aPTT

Seconds

30.8 (25.8–33.0)

59.6 (49.2–75.3)

Prothrombin time

Seconds

53.5 (41.0–68.5)

119 (101–138)

UFH anti-Xa activity

IU/mL

0.1 (0.1–0.1)

0.3 (0.2–0.45)

FVIII activity

%

253 (162–34)

394 (267–450)

vWF antigen

%

252 (196–372)

303 (208–392)

vWF activity

%

183 (132–244)

209 (161–276)

FVIII/vWF Ag ratio

0.9 (0.7–1.2)

0.9 (0.7–1.3)

Von Willebrand factor ratio

0.8 (0.7–0.8)

0.8 (0.7–0.8)

  1. aPTT activated partial thromboplastin time; FVIII coagulation factor VIII; UFH unfractionated heparin; vWF von Willebrand factor; vWF Ag von Willebrand factor antigen. Values represent the lowest and highest recorded measurements per patient during ECMO support. Data are presented as median values + IQR.