Table 1 Therapeutic effect of ZnO NPs on lung oxidative stress markers in P. equorum infected rats.

From: Nematocidal activity of zinc oxide nanoparticles synthesized using chicken egg albumin in lung and spleen of Parascaris equorum experimentally infected rats

Parameters

Groups

MDA

(nM/g.tissue)

GSH

(mM/g.tissue)

CAT

(U/min/g.tissue)

GST

(µM/g.tissue/min)

NO

(µM/g.tissue)

Noninfected groups

Control

1.89 ± 0.08

2.63 ± 0.23

231.08 ± 14.77

0.69 ± 0.08

538.12 ± 18.66

ZnO NPs (30 mg/kg)

2.07 ± 0.30

2.39 ± 0.16

216.20 ± 4.67

0.59 ± 0.02

584.25 ± 17.29

ZnO NPs (60 mg/kg)

1.95 ± 0.11

2.57 ± 0.04

229.57 ± 4.00

0.64 ± 0.03

544.43 ± 15.24

Infected groups

Vehicle

5.66 ± 0.12a

1.53 ± 0.12a

120.46 ± 6.42a

0.35 ± 0.01a

1,295.51 ± 11.66a

ZnO NPs (30 mg/kg)

3.73 ± 0.15b

1.84 ± 0.15b

152.45 ± 16.29b

0.45 ± 0.03b

917.99 ± 17.66b

ZnO NPs (60 mg/kg)

2.96 ± 0.30b

2.31 ± 0.12b

217.69 ± 18.22b

0.55 ± 0.03b

723.72 ± 14.14b

  1. Results are expressed as mean ± SE in each group.
  2. a: significant at (P < 0.05) compared to control group.
  3. b: significant compared to vehicle group.