Fig. 5

FAM172A regulates EOC cell proliferation through the PI3K/AKT signaling pathway. (A, B) Colony formation assay (A) and CCK-8 assay (B) evaluating the effect of PI3K activator (740Y-P) and inhibitor (LY294002) on FAM172A-induced proliferation. (C) Western blot analysis of proliferation-related proteins (PCNA, KI67). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.