Fig. 6 | Scientific Reports

Fig. 6

From: FAM172A promotes epithelial ovarian cancer progression and induces platinum resistance via the PI3K/AKT pathway

Fig. 6The alternative text for this image may have been generated using AI.

The PI3K/AKT-pathway mediates FAM172A effects on migration, invasion, and cisplatin resistance in EOC cells. (A, C) Wound healing assay (A) and Transwell assay. (B) Western blot analysis of epithelial–mesenchymal transition (EMT)-related proteins. (C) assessing the influence of PI3K activator and inhibitor on FAM172A-induced migration and invasion. (D) Effect of PI3K modulator treatment on FAM172A-mediated cisplatin resistance (IC₅₀). P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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