Fig. 2 | Scientific Reports

Fig. 2

From: Classifying the tumor immune microenvironment in cervical cancer based on nuclear cytoplasmic consistent genes

Fig. 2

Identification and functional characterization of Epi and NCCGs. (A) t-SNE plot depicting 34,293 Epi, colored according to eight distinct Epi clusters. (B) Proportional distribution of each Epi cluster across different sample groups. (C) Heatmap showing large-scale CNVs in single cells and single nuclei, inferred from scRNA-seq and snRNA-seq data, with Lym treated as the reference (top). Large-scale CNVs are observed in the Epi clusters (bottom). (D) Violin plot comparing the CNV values between Lym cells and Epi clusters. (E) Violin plot comparing the stem cell scores between Lym cells and Epi clusters. (F) Violin plots depicting the marker genes for different Epi clusters. (G) Heatmap showing the top 20 HALLMARK pathways across Epi clusters. (H) Venn diagram illustrating the overlap of differential genes identified in cancerous Epi versus normal cells from scRNA-seq and snRNA-seq, revealing the NCCGs. (I) Bubble diagram depicting the top 8 KEGG pathways and GO biological processes (bp) terms identified in NCCGs.

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