Fig. 6 | Scientific Reports

Fig. 6

From: In vivo, in silico effects of sakuranetin as a multi-target nutraceutical against PTZ-induced seizures via GABA restoration and BDNF/TrkB activation

Fig. 6

Effect of sakuranetin on pro-inflammatory cytokines in the brain: A) interleukin-6 (IL-6), B) interleukin-1β (IL-1β), and C) tumor necrosis factor-alpha (TNF-α) in PTZ-induced mice using enzyme-linked immunosorbent assay (ELISA) kits. Values are expressed as mean ± SEM (n = 6). Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test (#P < 0.001 PTZ vs. control; *P < 0.05, **P < 0.01 vs. PTZ).

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