Table 4 Proportion of the effect of trajectories of poverty and family adversity on young people’s mental health (age 17) due to mediation and interaction with perceived emotional support, weighted sample.

From: Perceived emotional support mediates the association between childhood family adversity and adolescent mental health in the UK millennium cohort

Component

Risk ratio

(95% CI)

TE

2.58

(2.09 to 3.06)

Excess Relative risk (TE-1)

1.58

(1.09 to 2.07)

Four-way decomposition (excess relative risk)

  

Proportional Attributable

(95% CI)

CDE

1.37

(0.92 to 1.82)

87%

(78% to 95%)

INTref

0.15

(0.03 to 0.27)

10%

(2% to 16%)

INTmed

0.04

(0.01 to 0.08)

3%

(0% to 5%)

PIE

0.02

(−0.0 to 0.04)

0%

(−0% to 2%)

Total excess relative risk

1.58

(1.09 to 2.06)

100%

 

Proportion eliminated, PE (INTref + INTmed + PIE)

  

13%

(5% to 22%)

Differential exposure (PIE + INTmed)

  

3%

(1% to 6%)

Differential susceptibility (INTref + INTmed)

  

13%

(5% to 23%)

  1. Note: TE = total effect; Excess relative risk = proportion of the total effect (TE − 1) that can be attributed to each component in the four-way decomposition; CDE = controlled direct effect (Due neither to mediation nor interaction); INTref = reference interaction (Due to interaction only); INTmed = mediated interaction (Due to mediation and interaction); PIE = pure indirect effect (Due to mediation only); Mediator level in CDE has been set to the optimal value of emotional support (i.e., score ranged from 3 to 9); PE = Proportional eliminated. Model adjusted for child sex, maternal education, ethnicity and lone parenthood.