Fig. 7

Enrichment analysis and correlation analysis of DEGs function and pathway of AVEN in LUAD. (A) A total of 503 up-regulated and 6205 down-regulated genes were identifed as being statistically signifcant between AVEN high expression and low expression groups. (B) Gene Ontology term and Kyoto Encyclopedia of Genes and Genomes pathway analyses of AVEN-related genes in LUAD. (C, D) GSEA function and pathway enrichment analysis of AVEN-related genes in LUAD. (E) Enrichment network of 21 HUB-related genes. (F) Heat map of co-expression of AVEN and 21 HUB genes in LUAD. (G) Heat map of correlation between AVEN and 21 HUB genes in LUAD. (H) Structure of AVEN.