Fig. 1 | Scientific Reports

Fig. 1

From: A simple method that doubles learning speed for mice in touchscreen-based visual discrimination

Fig. 1

Improved performance in the 1-pair VD task with multiple-touch protocols. (A) Behavioral sequences in a trial of the 1-pair visual discrimination (VD) task. The mouse selects and touches one of two stimulus patterns displayed in separate windows. A correct choice (S+) results in a reward pellet and a tone, while an error choice (S-) triggers a buzzer and a 10-s intertrial interval (ITI) before the next trial. (B) The task flowchart for the two-touch (2T) protocol. Mice were required to touch the same stimulus twice in succession to confirm a choice. (C) Task performance under 1 T, 2 T, and 3 T protocols, showing the across-animal percentage of correct responses over training sessions. Small pale symbols and lines represent individual animals’ performance, while large symbols represent the across-animal average. (D) Number of sessions required to reach the criterion (>75% correct for two consecutive sessions) for individual mice. NR denotes “not reaching the criterion” by Session 11. Horizontal bars represent median values. *p < 0.05 by Dunn’s multiple comparisons test. (E) Highest performance achieved by individual mice across training sessions. Horizontal bars indicate mean values. N = 9 (1T), 9 (2T), and 7 (3T) mice.

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