Table 2 Effect of different administration of STZ on the serum values of AST and ALT in male Sprague-Dawley rats.

From: Dose dependent toxicity of streptozotocin inducing diabetic complications in male Sprague Dawley rats with metabolic biochemical histopathological effects

 

AST(U/L)

ALT(U/L)

Normal group

23 ± 2

26 ± 3

STZ 45 mg/kg

57 ± 5a

55 ± 4a

STZ 60 mg/kg

75 ± 3b

85 ± 4b

  1. Rats were received single dose of STZ (45 or 60 mg/kg i.p.) to induce DM. Serum values of AST and ALT was evaluated. Results are expressed as mean ± SD (n = 8). aSignificant difference from normal group p < 0.05. bSignificant difference from STZ (45mg/kg) group p < 0.05.
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