Fig. 6
Protein-protein interaction (PPI) network and immune infiltration analysis. (a) PPI network diagram illustrating the interactions among differentially expressed autophagy-related genes (DE-ARGs). The nodes represent genes or proteins, and differently colored nodes indicate distinct functional modules or clusters. (b) PPI Network of 11 target genes. (c) Clustering heatmap presenting immune cell infiltration levels across different samples. The color gradient from blue to red represents infiltration levels from low to high. (d) Boxplot comparing the expression levels of different immune cells between the normal group (blue) and the ulcerative colitis (UC) group (red). (e) Heatmap illustrating the correlation between the target genes (PEA15, CASP4, CASP1, and SERPINA1) and the infiltration levels of different immune cells. The color gradient from blue to red represents the degree of correlation from negative to positive, with deeper colors indicating stronger correlations.
