Fig. 4 | Scientific Reports

Fig. 4

From: Comparative study of analytical methods for assessing mRNA integrity and identification of functional mRNA oligomers

Fig. 4

Properties of the protein expressed from monomer and dimer fractions. (A) Flow cytometric analysis, (B) Western blot analysis (this is a cropped version of the original blot image; the uncropped original blot is presented in Supplementary Figure S7), and (C) Reactogenicity studies. DP, Drug Product; DS, Drug Substance; kDa, kilo Dalton; Mw, molecular weight; Rg, radius of gyration. DS, Drug Substance; Dim, dimer; IFN, interferon; Mon, monomer; NF-κB, nuclear factor kappa B; THP-1, human leukemia monocytic cell line.

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