Fig. 4 | Scientific Reports

Fig. 4

From: Compatibility of fast tissue clearing with targeted fluorescence imaging and pathology analysis using clinical head and neck cancer biopsies

Fig. 4

Overview of representative examples of fluorescence images obtained for control, not cleared, (top 2 rows), normal cleared (middle 2 rows) and fast cleared biopsies (bottom 2 rows). For each clearing approach both tumor tissue, containing the fluorescent tracer, and healthy tissue, obtained from the same patient, were analyzed. Column 3–5 show images obtained with the fluorescence imaging system at different time points: before, 1 and 28 days after tissue clearing. The 6th column shows the confocal imaging results 7 days after clearing.

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