Fig. 3

1,25(OH)₂D₃ affected the diversity of intestinal microbiota and changed the dominant bacterial genera. Venn diagram (a), Shannon index (b), Principal Coordinate Analysis (PCoA) based on the unweighted Unifrac distance (c), and relative abundance at the phylum level (d) of microbiota among groups. Linear discriminant analysis Effect Size (LEfSe) was used to analyze the most differential taxa in the different groups (e). The enriched taxa with an LDA score > 2 in each group are shown in different colors (f).