Fig. 2 | Scientific Reports

Fig. 2

From: Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma

Fig. 2

Transcriptomic analysis of A549 cells treated with SH (n = 5 (independent cell cultures)). (A) PCA scatter plot illustrating transcriptome variations between the Model and Shikonin groups. (B) Volcano plot showing differentially expressed genes (DEGs) between Model versus Shikonin. (C) Quantities of differentially expressed genes, where up-regulated genes are indicated in red and down-regulated genes are shown in blue. (D) Top 20 KEGG pathway enrichments for differentially expressed genes (Model vs. Shikonin).

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