Table 4 The grading of chemical phlebitis assessed by phlebitis scale on day 7.

From: Symptomatic and pathological features in chemical phlebitis rat model by injection vinorelbine via dorsal pedal vein

Group

mg/ml

Dose

mg/kg

Grade

P

0

I

II

III

IV

0

0

8 (100.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

-

1

0.32

8 (100.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000

2

0.65

3 (37.5%)

5 (62.5%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0.023*

3

0.94

0 (0.0%)

2 (25.0%)

4 (50.0%)

2 (25.0%)

0 (0.0%)

< 0.001***

4

1.25

0 (0.0%)

0 (0.0%)

2 (25.0%)

4 (50.0%)

2 (25.0%)

< 0.001***

5

1.56

0 (0.0%)

0 (0.0%)

0 (0.0%)

3 (37.5%)

5 (62.5%)

< 0.001***

  1. Compared with 0 mg/mL group, *p < 0.05, ***p < 0.001.