Fig. 2

Effect of Bacillus coagulans ATCC 7050 treatment on working memory and locomotor activity in Aβ1–42-injected rats evaluated by Y-maze test. (a) Spontaneous alternation percentage in the Y-maze as an index of spatial working memory. (b) Total arm entries in the Y-maze as an index of locomotor activity. Rats were assigned to Sham, Alzheimer’s disease (AD), B. coagulans only (BC), and AD treated with B. coagulans (AD + BC) groups (n = 8 per group). ** P < 0.01 vs. Sham; # P < 0.05, ## P < 0.01 vs. AD. All values are expressed as mean ± SEM.