Fig. 4 | Scientific Reports

Fig. 4

From: Influence of infant fucosyltransferase polymorphisms on the association of maternal secretor status with child outcomes: the Ulm birth cohort studies

Fig. 4

Adjusted associations between infant fucosyltransferase-2 (FUT2) heterozygosity with health outcomes in the first 2 years of life, stratified by secretor and non-secretor milk in the Ulm Birth Cohorts. Results are presented as odds ratios (AD) and risk ratios (infections) with 95% CI. Models adjusted for child sex, maternal allergy (AD only), delivery mode (infections only), maternal milk and/or ABO blood group. Reference groups: homozygous secretors (SeSe) in secretor milk and non-secretors (sese) in non-secretor milk. Bonferroni-adjusted significance threshold: α = 0.0035. Bonferroni-adjusted level of statistical significance is α = 0.05/14 = 0.0035. Abbreviations: AD, atopic dermatitis; OM, otitis media; LRTI, lower respiratory tract infections; URTI, upper respiratory tract infections; CI, confidence interval; FUT2, fucosyltransferase-2; SNP, single nucleotide polymorphism; HMO, human milk oligosaccharide; SPATZ, Ulm SPATZ Health Study; UBCS, Ulm Birth Cohort Study.

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