Table 1 Asthmatic patients and subject demographics.
Characteristic | Bronchial asthma (BA) patients | Control group |
|---|---|---|
Number (n) | 78 | 78 |
Gender | ||
Male (n/%) | 41 / 53% | 40 / 51% |
Female (n/%) | 37 / 47% | 38 / 49% |
Age (years) | 45 (18–65) | 46 (18–65) |
Smoking history | ||
Never | 30 | 40 |
Current | 10 | 8 |
Ex-smokers | 10 | 10 |
BMI (body mass index) | ||
Normal weight 18.5–24.9 (n / %) | 0 | 68 / 87% |
Overweight 25.0–29.9 (n / %) | 2 / 2% | 8 / 10% |
Obesity class I 30.0–34.9 (n / %) | 5 / 7% | 1 / 1.5% |
Obesity class II 35.0–39.9 (n / %) | 15 / 20% | 1 / 1.5% |
Obesity class III > 40 (n / %) | 53 / 71% | 0 |
Eosinophilic asthma (n /%) | 43 / 61% | N/A |
Non-eosinophilic asthma (n / %) | 28 / 39% | N/A |
Types of BA asthma | ||
J45.0 Allergic (J45.0) | 18 / 32% | 0 |
J45.8 Mixed (J45.8) | 34 / 61% | 0 |
J45.9 Non-identified (J45.9) | 4 / 7% | 0 |
Peripheral blood counts | ||
Lymphocytes, % / cell/µl | 49%/4031.8 | 19,81% /1484.55 |
Neutrophils, % / cell/µl | 43%/ 3493.4 | 53.78% / 2455.24 |
Eosinophils, % / cell/µl | 7.5% / 613.1 | 3.83% / 89.65 |
Basophils, % / cell/µl | 0.5%/27.8 | 1.38% / 32.13 |
Concomitant diseases | ||
AERD# (n /%) | 12 / 41% | 0 |
Atopic dermatitis (n /%) | 8 / 28% | 0 |
Allergic rhinitis (n /%) | 9 / 31% | 0 |
Therapies | ||
SABA## (n /%) | 20 / 25.6% | 0 |
Low dose ICS (≤ 250 µg fluticasone equivalent)* (n /%) | 24 / 30.76% | 0 |
ICS, moderate dose ** (n /%) | 28 / 35.9% | 0 |
High dose ICS (> 500 µg fluticasone equivalent)*** (n /%) | 26 /33.3 | 0 |
LABA# (n /%) | 58 / 74.4% | 0 |
Tiotropium bromide (n /%) | 22 / 28.2% | 0 |