Table 1 NIHSS scale score distribution at 24 h, according to baseline data, in the derivation cohort (n = 123).

From: NIHSS mismatch as a predictor of early neurological improvement after mechanical thrombectomy

Variables

NIHSS scale at 24 h

Median (IQR)

P

Demographic data and comorbidities

Age >65

Yes

8 (16)

0.072

No

4 (14)

Male sex, n (%)

Yes

6 (14)

0.849

No

7 (17)

Previous mRS < 2, n (%)

Yes

6 (15)

0.168

No

13.5 (15)

Arterial hypertension, n (%)

Yes

9 (14)

0.108

No

5 (15)

Dyslipidemia, n (%)

Yes

8 (16)

0.308

No

6 (14)

Diabetes mellitus, n (%)

Yes

13.5 (14)

0.009

No

5 (14)

Smoking, n (%)

Yes

3.5 (11)

0.091

No

8 (18)

Alcohol abuse, n (%)

Yes

6.5 (17)

0.313

No

7 (15)

Atrial fibrillation, n (%)

Yes

5.5 (14)

0.492

No

8 (16)

Coronary heart disease, n (%)

Yes

6 (20)

0.977

No

7 (15)

Previous stroke, n (%)

Yes

4 (6)

0.181

No

8 (17)

Prior treatments

Antiplatelet Agents, n (%)

Yes

8.5 (16)

0.334

No

5 (11)

Anticoagulants, n (%)

Yes

4 (19)

0.313

No

5 (11)

Statins, n (%)

Yes

5 (18)

0.587

No

6.5 (14)

Neuroimaging

NCCT-ASPECTS at 24 h

9–10

1 (4)

< 0.001

6–8

5 (11)

0–5

19 (10)

Proximal thrombus location on admission

ICA

13 (15)

0.062

M1

6 (14)

M2

5 (11)

Lateralization of the occlusion

Left

11 (16)

0.012

Right

5 (10)

Collaterals on CTA on admission*

Good

13 (18)

0.331

Fair

6 (13)

Poor

5 (15)

Parenchymal hemorrhagic transformation (PH1/PH2) at 24 h**

Yes

19 (6)

< 0.001

No

5 (13)

Cerebral edema with midline shift (grade 3) at 24 h, n (%)

Yes

21 (5)

< 0.001

No

5 (12)

  1. * Dawn trial criteria18; **Heidelberg bleeding classification19; SITS-MOST criteria20.