Table 2 Basal data of the validation cohort (n = 185) according with early neurological improvement (ENI).
From: NIHSS mismatch as a predictor of early neurological improvement after mechanical thrombectomy
All (n = 185) | Early neurological improvement | |||
|---|---|---|---|---|
Yes (n = 64) | No (n = 121) | P | ||
Demographic data and comorbidities | ||||
Male sex, n (%) | 105 (56.8) | 34 (53.1) | 71 (58.7) | 0.468 |
Age, mean (SD), years | 71.4 (13.1) | 68.6 (14.6) | 72.7 (12.2) | 0.174 |
Previous mRS < 2, n (%) | 120 (64.9) | 44 (68.8) | 76 (62.8) | 0.421 |
Arterial hypertension, n (%) | 166 (89.7) | 55 (85.9) | 111 (91.7) | 0.217 |
Dyslipidemia, n (%) | 85 (45.9) | 32 (50) | 53 (43.8) | 0.421 |
Diabetes mellitus, n (%) | 61 (33) | 17 (26.6) | 44 (36.4) | 0.177 |
Smoking, n (%) | 37 (20) | 12 (18.8) | 25 (20.7) | 0.757 |
Alcohol abuse, n (%) | 15 (8.1) | 4 (6.3) | 11 (9.1) | 0.501 |
Atrial fibrillation, n (%) | 96 (51.9) | 34 (53.1) | 62 (51.2) | 0.807 |
Coronary heart disease, n (%) | 32 (17.3) | 6 (9.4) | 26 (21.5) | 0.038 |
Previous stroke, n (%) | 15 (8.1) | 8 (12.5) | 7 (5.8) | 0.111 |
Prior treatments | ||||
Antiplatelet Agents, n (%) | 74 (40) | 23 (35.9) | 51 (42.1) | 0.412 |
Anticoagulants, n (%) | 25 (13.5) | 10 (15.6) | 15 (12.4) | 0.541 |
Statins, n (%) | 99 (53.5) | 32 (50) | 67 (55.4) | 0.486 |
Stroke severity | ||||
NIHSS on admission, median (IQR) | 17 (7) | 18 (8) | 16 (6) | 0.022 |
NIHSSexpected, median (IQR) | 4 (4) | 3 (4) | 4 (4) | 0.004 |
NIHSSmismatch%, median (IQR), % | 77.4 (22.3) | 83.1 (17.6) | 72 (21.3) | < 0.001 |
NIHSSmismatch% >72, n (%) | 85 (45.9) | 45 (70.3) | 40 (33.1) | < 0.001 |
Extended time window (6–24 h), n (%) | 53 (28.6) | 18 (28.1) | 35 (28.9) | 0.909 |
Neuroimaging on admission | ||||
NCCT-ASPECTS, median (IQR) | 9 (2) | 9 (2) | 8 (3) | < 0.001 |
Proximal thrombus location M2 M1 ICA | 19 (10.3) 126 (68.1) 40 (21.6) | 4 (6.3) 46 (71.9) 14 (21.9) | 15 (12.4) 80 (66.1) 26 (21.5) | 0.418 |
Side of the occlusion: Left, n (%) | 103 (55.7) | 38 (59.4) | 65 (53.7) | 0.461 |
Collaterals grade on CTA-SI* on admission Good, n (%) Fair, n (%) Poor, n (%) | 38 (20.5) 121 (65.4) 26 (14.1) | 17 (26.6) 39 (60.9) 8 (12.5) | 21 (17.4) 82 (67.8) 18 (14.9) | 0.334 |
Thrombolysis, n (%) | 120 (64.9) | 44 (68.8) | 76 (62.8) | 0.421 |
Mechanical thrombectomy data | ||||
Onset-to-groin puncture time, median (IQR), min | 265 (264) | 210 (168) | 298.5 (311) | 0.004 |
Door-to-groin puncture time, median (IQR), min | 90 (47) | 86 (35) | 95 (63.5) | 0.132 |
Number of passes, median (IQR) | 3 (3) | 3 (4) | 3 (3) | 0.082 |
Reperfusion-mTICI 2bc3, n (%) | 164 (88.6) | 60 (93.8) | 104 (86) | 0.112 |
Stroke aetiology (TOAST), n (%) | 0.456 | |||
Large-vessel occlusive | 43 (23.2) | 15 (23.4) | 28 (23.1) | |
Cardioembolic | 111 (60) | 40 (62.5) | 71 (58.7) | |
Other | 3 (1.6) | 2 (3.1) | 1 (0.8) | |
Unknown | 28 (15.1) | 7 (10.9) | 21 (17.4) | |
Blood pressure on admission | ||||
Systolic, mean (SD), mmHg | 151.3 (28.9) | 148.3 (25.3) | 152.8 (30.5) | 0.383 |
Diastolic, mean (SD), mmHg | 81 (17.5) | 80 (17) | 81 (17.8) | 0.674 |
Glycaemia on admission, mean (IQR) mg/dL | 141.2 (53.6) | 133.4 (42.5) | 145 (58.2) | 0.095 |
