Table 1 Baseline characteristics of open angle glaucoma patients stratified by depression status.

From: Independent associations of physical activity and depression with open-angle glaucoma in a population-based analysis

 

Non-depression

Depression

P-value

(N = 71792)

(N = 25825)

 

Age (year, N)

58.2 ± 12.6

64.0 ± 11.3

< 0.001

< 40

5982 ( 8.3%)

795 ( 3.1%)

< 0.001

40–49

11,874 (16.5%)

2150 ( 8.3%)

 

50–59

18,705 (26.1%)

4993 (19.3%)

 

60–69

20,452 (28.5%)

8568 (33.2%)

 

70–79

12,954 (18.0%)

8149 (31.6%)

 

≥ 80

1825 ( 2.5%)

1170 ( 4.5%)

 

Sex

  

< 0.001

 Male

42,834 (59.7%)

12,297 (47.6%)

 

 Female

28,958 (40.3%)

13,528 (52.4%)

 

Comorbidities

   

 Hypertension

31,483 (43.9%)

13,838 (53.6%)

< 0.001

 Diabetes

13,581 (18.9%)

6044 (23.4%)

< 0.001

 Dyslipidemia

24,877 (34.7%)

10,516 (40.7%)

< 0.001

CCI

1.9 ± 1.9

2.6 ± 2.1

< 0.001

0

18,432 (25.7%)

3655 (14.2%)

< 0.001

1

18,822 (26.2%)

5267 (20.4%)

 

2

13,413 (18.7%)

5343 (20.7%)

 

≥ 3

21,125 (29.4%)

11,560 (44.8%)

 

BMI (kg/m2)

24.1 ± 3.1

24.0 ± 3.1

0.082

Alcohol consumption

  

< 0.001

 Non

40,956 (57.0%)

17,641 (68.3%)

 

 Mild

18,913 (26.3%)

5035 (19.5%)

 

 Moderate

7055 ( 9.8%)

1753 ( 6.8%)

 

 Severe

4868 ( 6.8%)

1396 ( 5.4%)

 

Smoking

  

< 0.001

 Never smoker

43,289 (60.3%)

17,758 (68.8%)

 

 Ex-smoker

16,111 (22.4%)

4683 (18.1%)

 

 Current smoker

12,392 (17.3%)

3384 (13.1%)

 

Low income

  

< 0.001

 The bottom 20% or below

9854 (13.7%)

4087 (15.8%)

 

 Others

61,938 (86.3%)

21,738 (84.2%)

 

Physical activity level

   

Before OAG diagnosis

  

0.065

 Low level

32,363 (45.1%)

11,469 (44.4%)

 

 High level

39,429 (54.9%)

14,356 (55.6%)

 

After OAG diagnosis

  

0.001

 Low level

30,936 (43.1%)

11,452 (44.3%)

 

 High level

40,856 (56.9%)

14,373 (55.7%)

 
  1. Data are expressed as the mean ± the standard deviation or as n (%). The P-value is derived from the student t-test and the Chi-square test. BMI, body mass index; CCI. Charlson comorbidity index; OAG. open angle glaucoma. Patients who developed depression after OAG diagnosis were older, more often female, and had a higher prevalence of comorbidities compared with those without depression.