Fig. 5
From: Functional PET for mapping metabolic dynamics in Parkinson’s disease
Seed-based metabolic and hemodynamic networks in PwPD with and without cognitive impairment and healthy controls. (a) Group-level metabolic (fPET) and hemodynamic (fMRI) seed-based networks obtained by voxel-wise one-sample t-tests with respective subject-level contrast images for n = 11 HC, n = 9 PD-NC (fMRI: n = 7) and n = 5 PD-MCI. (b) Extracted fPET time course of the corresponding seed region with subject-level time courses (dotted line) and mean time course per group (filled line). Colorbar indicates t-values between 3 and 11 for comparability of the modalities. All images are shown in neurological display. Abbreviations: HC = control subjects, PD = Parkinson’s disease, ACC = anterior cingulate cortex, LPFC-R = right lateral prefrontal cortex, PCC = precuneus cortex, SMS = superior sensorimotor cortex, MCI = mild cognitive impairment, NC = normal cognition, ROI = region of interest.
