Table 2 Cytoplasmic Ca2+ transient parameters of TRPV1+/+ and TRPV1−/− adult mouse cardiomyocytes paced at 0.5–1 Hz.

From: TRPV1 deletion in male mice alters cardiomyocyte ultrastructure without affecting baseline cardiac function

 

0.5 Hz

1 Hz

TRPV1+/+

TRPV1−/−

TRPV1+/+

TRPV1−/−

FD

1.045 [1.006;1.088]

1.121 [1.028;1.021]

1.168 [1.067;1.277]

1.121 [1.028;1.198]

ΔF/F0

0,8179 [0,5927; 1,022]

0,8098 [0,4681;0.8693]

0.6778 [0.4599; 0.9801]

0.7142 [0.4801;0.8693]

AUC

0,4254 [0,3032; 0,5161]

0,3633 [0,2474; 0,4483]

0.2311 [0.1507;0.3005]

0.2304 [0.1656;0.2776]

TTP (s)

0,1962 [0.1039; 0,2698]

0,3667 [0,2536; 0,4796]****

0.1172 [0.1039;0.1462]

0.1386 [0.1167;0.197]**

t1/2 (s)

0,3898 [0,3326; 0,4619]

0,3449 [0,3111; 0,3972]

0.2867 [0.2527;0.3111]

0.2826 [0.2509;0.3238]

τ (s)

1,829 [1,759; 1,948]

1,673 [1,562; 1,761]****

0.9016 [0.8751;0.9095]

0.8734 [0.8219;0.9059]*

  1. Data are presented as median [25th percentile; 75th percentile]. FD diastolic efflux, ΔF/F0 peak amplitude, AUC area under the curve (systolic efflux), TTP time to peak, t1/2 half-time, τ Time to basal. Statistical comparison by Wilcoxon-Mann–Whitney non-parametric tests: ****p < 0,0001; **p < 0,01; *p < 0,05. At 0.5 Hz, n = 40 TRPV1+/+ and 28 TRPV1−/− cells from 4 mice; at 1 Hz, n = 58 TRPV1+/+ and 37 TRPV1−/− cells from 5 mice.
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