Fig. 3
From: The accumulation of extracellular K+ as in vivo model of epilepsy in CA1 pyramidal neurons
3D contour plots representing the total number of seconds in which [K+]e > 12 mM, during a series of 10 min simulations carried out by exploring a wide combination of τ2,3,4 decay time constants at low (left plot) and high (right plot) synaptic weight (30 and 60 nS, respectively). Values in the Z axis are color coded: the red area represents simulations reaching a depolarization block at any time during the 10 min stimulation, and dark purple represents simulations where the [K+]e never reached the 12 mM value. The white marker indicates the values used for the simulations shown in Fig. 4.
