Table 4 Analysis of factors associated with substandard Cmin in the TBI group. TBI, traumatic brain injury; IQR, interquartile range.

From: Effect of traumatic brain injury on the trough concentration of linezolid in patients with hospital-acquired pneumonia

Characteristics

TBI group (n = 46)

Non-TBI group (n = 46)

Statistics

P

Using mannitol and glycerol fructose, n (%)

24 (52.2)

3 (6.5)

18.706

< 0.001

Diabetes insipidus or using desmopressin, n (%)

1 (2.2)

0 (0.0)

0.000

> 0.999

Fluid intake in the 24 h before Cmin measurement (mL), median (IQR)

3381.0 (2880.0–3926.0)

2755.0 (2382.0–3155.0)

− 2.515

0.012

Fluid output in the 24 h before Cmin measurement (mL), median (IQR)

2540.0 (1500.0–3540.0)

1550.0 (1250.0–2300.0)

− 2.807

0.005