Fig. 3 | Scientific Reports

Fig. 3

From: Evolutionary analysis through structural modeling of FAM222 proteins reveals a novel disordered conserved domain in vertebrates that interacts with NLK

Fig. 3

Structural modeling of the conserved region in FAM222 proteins. (A) Representative structural models of hFAM222A and hFAM222B generated using AlphaFold3. Amino acid residues are colored based on their pLDDT scores, where values near 100 indicate high confidence and values near 0 indicate low confidence, as visualized in ChimeraX. (B and C) Structural models of the conserved domain in gnathostomes and cyclostomes, with their corresponding linear representations of secondary structure.

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