Table 2 Spearman´s correlation coefficients for the correlation of PCSK9 with different parameters.

From: Systemic PCSK9 elevation characterises autoimmune liver disease across sexes

Characteristics

PSC

females

PSC

males

PSC

males and

females

PBC

females

AIH

females

Age (years)

0.087

0.127

0.076

0.106

0.285

BMI (kg/m2)

-0.008

0.207

0.154

-0.120

-0.133

AST (U/L)

-0.391*

-0.011

-0. 090

0.188

-0.218

ALT (U/L)

-0.365

-0.080

-0.98

0.002

-0.345

GGT (U/L)

-0.173

0.021

0.015

0.127

-0.050

AP (U/L)

-0.370

-0.049

-0.116

0.243

-0.159

Bilirubin (mg/dL)

-0.264

0.252

0.123

0.271

-0.037

Bilirubin direct

(mg/dL)

-0.096

0.638*

0.493*

0.329

-0.252

Bilirubin

indirect

(mg/dL)

0.277

0.637*

0.479*

0.210

-0.342

LDL (mg/dL)

-0.286

0.104

-0.039

-0.037

0.216

Cholesterol

-0.333

0.162

-0.019

-0.015

0.393

Fibroscan

-0.011

0.066

0.034

0.158

0.130

MELD Score

-0.063

0.228

0.202

0.372

-0.082

  1. Correlations for PCSK9 in male and female patients as well as the entire primary sclerosing cholangitis (PSC) group, female patients with primary biliary cholangitis (PBC), and female patients with autoimmune hepatitis (AIH). * p < 0.05, ** p < 0.01.
  2. Alanine aminotransferase (ALT), alkaline phosphatase (AP), aspartate aminotransferase (AST), body mass index (BMI), gamma-glutamyl transferase (GGT), low-density lipoprotein (LDL), Model of End Stage Liver Disease (MELD).