Table 3 Multivariate logistic regression analysis of 19 features for lymph node metastasis in gastric cancer patients.

From: Interpretable machine learning analysis of clinicopathological and immunonutritional biomarkers for predicting lymph node metastasis in gastric cancer

 

Features

OR

95%CI

P value

1

T stage.T4

16.091

(9.711–26.661)

< 0.001a

2

T stage.T3

14.751

(8.326–26.135)

< 0.001a

3

MTD

2.425

(1.682–3.497)

< 0.001

4

T stage.T2

3.667

(2.138–6.291)

< 0.001a

5

Poorly grade

5.891

(1.477–23.491)

0.004b

6

Moderately grade

3.322

(0.919–12.015)

0.067

7

Lauren.Mixed

0.632

(0.35–1.14)

0.127c

8

PAR

1.186

(0.938–1.499)

0.154

9

CEA

1.114

(0.953–1.302)

0.176

10

SII

0.854

(0.54–1.349)

0.498

11

Lauren.Diffuse

0.822

(0.451-1.5)

0.524

12

RAR

0.886

(0.601–1.305)

0.54

13

PLR

1.068

(0.747–1.527)

0.717

14

PT

0.976

(0.838–1.136)

0.751

15

Age

0.998

(0.982–1.014)

0.76

16

FIB

1.02

(0.864–1.205)

0.811

17

AISI

1.044

(0.731–1.49)

0.814

18

PNI

0.978

(0.737–1.296)

0.875

19

HRR

1.018

(0.38–2.729)

0.971

  1. aT1 stage as control; bWell group as control; cIntestinal group as control. T stage, tumor stage according to AJCC staging system; MTD, maximum tumor diameter; Lauren classification, histological classification (Mixed, Diffuse, and Intestinal type); Grade, histological grade (Poorly, Moderately, and Well differentiated); CEA, carcinoembryonic antigen; PAR, platelet-to-albumin ratio; SII, systemic immune-inflammation index; RAR, red blood cell distribution width-to-albumin ratio; PLR, platelet-to-lymphocyte ratio; PT, prothrombin time; FIB, fibrinogen; AISI, aggregate index of systemic inflammation; PNI, prognostic nutritional index; HRR, hemoglobin-to-red blood cell distribution width ratio; OR, odds ratio; CI, confidence interval.
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