Fig. 6

Effect of RP11 on the immune microenvironment and drug safety evaluation of ES-Cu. (A) IL-6 content of each group. (B) IL-8 content of each group. (C) HE staining of heart, liver, spleen, lung and kidney sections from the mice. (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001). Data are presented as mean ± SD with 95% confidence intervals for pairwise differences; Bonferroni post-hoc correction was applied and adjusted P values are indicated in the figure.