Table 2 Critical functions of ASCL2 in human cancers.

From: ASCL2 contributes to clinical assessments of breast cancer and mediates tumor progression via the interaction with CLDN3

Cancer type

PMID

Expression

Function

Colon cancer

39,895,630

Up-regulated

Oncogenic properties

Colorectal cancer

37,591,954

Up-regulated

Immune excluded microenvironment

Colorectal cancer

36,824,410

Up-regulated

Stemness

Prostate cancer

38,064,349

Up-regulated

Neuroendocrine differentiation

Stomach adenocarcinoma

36,008,864

Up-regulated

Inflammation regulation

Pancreatic adenocarcinoma

38,955,307

Up-regulated

Oncogenic properties