Table 2 Results of GO and KEGG enrichment analysis for ERSRDEGs.
Ontology | ID | Description | GeneRatio | BgRatio | pvalue | padj | qvalue |
|---|---|---|---|---|---|---|---|
BP | GO:1,990,266 | neutrophil migration | 6/10 | 129/18,888 | 1.85E-11 | 2.13E-08 | 5.83E-09 |
BP | GO:0097530 | granulocyte migration | 6/10 | 154/18,888 | 5.45E-11 | 3.13E-08 | 8.57E-09 |
BP | GO:0050900 | leukocyte migration | 7/10 | 396/18,888 | 1.92E-10 | 7.36E-08 | 2.01E-08 |
BP | GO:0071222 | cellular response to lipopolysaccharide | 6/10 | 225/18,888 | 5.40E-10 | 1.49E-07 | 4.07E-08 |
BP | GO:0071219 | cellular response to molecule of bacterial origin | 6/10 | 238/18,888 | 7.57E-10 | 1.49E-07 | 4.07E-08 |
CC | GO:0009897 | external side of plasma membrane | 3/10 | 405/19,894 | 9.04E-04 | 1.45E-02 | 1.05E-02 |
MF | GO:0005125 | cytokine activity | 9/10 | 238/18,522 | 8.12E-17 | 2.52E-15 | 8.55E-16 |
MF | GO:0005126 | cytokine receptor binding | 9/10 | 273/18,522 | 2.84E-16 | 4.41E-15 | 1.50E-15 |
MF | GO:0070851 | growth factor receptor binding | 4/10 | 138/18,522 | 5.98E-07 | 6.18E-06 | 2.10E-06 |
MF | GO:0008009 | chemokine activity | 3/10 | 49/18,522 | 2.06E-06 | 1.60E-05 | 5.42E-06 |
MF | GO:0042379 | chemokine receptor binding | 3/10 | 74/18,522 | 7.20E-06 | 4.46E-05 | 1.52E-05 |
KEGG | hsa04060 | Cytokine-cytokine receptor interaction | 9/10 | 298/8848 | 4.81E-13 | 3.80E-11 | 1.27E-11 |
KEGG | hsa05323 | Rheumatoid arthritis | 7/10 | 94/8848 | 1.42E-12 | 5.63E-11 | 1.87E-11 |
KEGG | hsa04657 | IL-17 signaling pathway | 6/10 | 95/8848 | 2.65E-10 | 6.98E-09 | 2.32E-09 |
KEGG | hsa04668 | TNF signaling pathway | 6/10 | 119/8848 | 1.05E-09 | 2.07E-08 | 6.90E-09 |
KEGG | hsa05133 | Pertussis | 5/10 | 78/8848 | 1.14E-08 | 1.80E-07 | 5.99E-08 |