Table 2 CCTA and CT-MPI characteristics in patients with and without DM. Data are presented as mean ± SD or median (interquartile range). CCTA = coronary computed tomography angiography, CT = computed tomography, CT-MPI = computed tomography myocardial perfusion imaging, DM = diabetes mellitus, CAD-RADS = Coronary Artery Disease—Reporting and Data System, CAD = coronary artery disease, CACS = Coronary Artery Calcium Scoring, SIS = segment involvement score, SSS = segment stenosis score, HRP = high-risk plaque, MBF = myocardial blood flow.
Total (n = 331) | DM (n = 92) | Non-DM (n = 239) | p | |
|---|---|---|---|---|
Coronary CT angiography | ||||
CAD-RADS | 0.406 | |||
0 | 17 (5.1%) | 2 (2.2%) | 15 (6.3%) | |
1 | 30 (9.1%) | 6 (6.5%) | 24 (10.0%) | |
2 | 84 (25.4%) | 22 (23.9%) | 62 (25.9%) | |
3 | 136 (41.1%) | 44 (47.8%) | 92 (38.5%) | |
4 | 51 (15.4%) | 14 (15.2%) | 37 (15.5%) | |
5 | 13 (3.9%) | 4 (4.3%) | 9 (3.8%) | |
Obstructive CAD | 200 (60.4%) | 62 (67.4%) | 138 (57.7%) | 0.108 |
Cumulative vessels | 0.287 | |||
0 | 130 (39.3%) | 30 (32.6%) | 100 (41.8%) | |
1 | 142 (42.9%) | 41 (44.6%) | 101 (42.3%) | |
2 | 41 (12.4%) | 14 (15.2%) | 27 (11.3%) | |
3 | 17 (5.1%) | 7 (7.6%) | 10 (4.2%) | |
CACS | < 0.001 | |||
0 | 87 (26.3%) | 11 (12.0%) | 76 (31.8%) | |
1–99 | 107 (32.3%) | 38 (41.3%) | 69 (28.9%) | |
100–399 | 71 (21.5%) | 17 (18.5%) | 54 (22.6%) | |
≥ 400 | 66 (19.9%) | 26 (28.3%) | 40 (16.7%) | |
SIS ≥ 4 | 219 (66.2%) | 73 (79.3%) | 146 (61.1%) | 0.002 |
SSS ≥ 6 | 106 (32.0%) | 41 (44.6%) | 65 (27.2%) | 0.002 |
HRP | 196 (59.2%) | 61 (66.3%) | 135 (56.5%) | 0.103 |
Stress dynamic CT-MPI | ||||
Global MBF value | 131.7 (113.1,149.8) | 120.3 (109.0,139.6) | 135.1 (115.4,151.1) | 0.001 |
Lowest MBF value | 104.0 ± 24.6 | 99.2 ± 22.2 | 105.8 ± 25.2 | 0.029 |
Ischemic score | 0.035 | |||
0–3 | 152 (45.9%) | 33 (35.9%) | 119 (49.8%) | |
4–7 | 94 (28.4%) | 30 (32.6%) | 64 (26.8%) | |
8–11 | 36 (10.9%) | 16 (17.4%) | 20 (8.4%) | |
≥ 12 | 49 (14.8%) | 13 (14.1%) | 36 (15.1%) | |