Fig. 1
From: Antitumor effects of a novel glucose-conjugated bacteriochlorin for photodynamic therapy
Chemical structures of photosensitizers and synthesis of 5,10,15,20-tetrakis(4-(β-D-glucopyranosylthio)-2,3,5,6-tetrafluorophenyl)-2,3-(methano(N-methyl)iminomethano)bacteriochlorin (Glc-TFPB). (a) Glc-TFPB: 5,10,15,20-tetrakis(4-(β-D-glucopyranosylthio)-2,3,5,6-tetrafluorophenyl)-2,3-(methano(N-methyl)iminomethano)bacteriochlorin. (b) TS: Mono-L-aspartyl chlorin e6. (c) Glucose-conjugated porphyrin (1) was converted into a bacteriochlorin derivative (2) via reduction with p-toluenesulfonyl hydrazide, and subsequent deacetylation of the glucose moiety yielded glucose-conjugated bacteriochlorin (3).
