Fig. 2 | Scientific Reports

Fig. 2

From: Cilazapril and benazepril mitigate neurodegeneration and α-synuclein accumulation in a cellular model of parkinson’s disease

Fig. 2The alternative text for this image may have been generated using AI.

(a) D1A Receptor-Interaction (2D View) Benazepril interacts with Asp187 and Trp321 via hydrogen bonding and differs in its binding mode compared with C. Hydrophobic interactions contribute to its stabilization at the active site of the receptor. (b) Receptor interaction (3D view) The binding site of benazepril within the D1A receptor is depicted, highlighting the key residues involved in its interaction. Compared with that of C, the binding pocket orientation emphasizes its unique conformation.

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