Fig. 3 | Scientific Reports

Fig. 3

From: Treadmill exercise ameliorates atherogenesis and vascular inflammation in ApoE−/− mice via circulating exosome-derived let-7c-5p

Fig. 3

Exercise reduces aortic plaque formation. (A) Representatives of morphometric en face Oil Red O-stained lesions (red) in the aorta and statistical results (n = 7 per group). (B) The aortic arches were exposed, photographed and representative H&E staining images of the brachiocephalic arteries from three groups. (C) Representative images of Oil Red O staining, Masson staining and CD68 IHC staining in aortic root cross-sections. (D) Quantification of the Oil red area (n = 7–12 per group). (E) Quantification of collagen content (n = 7–12 per group). (F) Quantification of CD68 positive area (n = 7–12 per group). *P < 0.05,  *P < 0.01, ***P < 0.001.

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